Updated January 2010



NCBI databases : 55767 nucleotide (54309 ESTs)/1 genome/650 protein entries
Genome Project 12879: 265,503 records (WGS/EST/454/BES) in the trace archives

Short Read Archive (SRA): 454 data projects: 23 Gbases gDNA, 714 Mbases cDNA


 Introduction
-An international consortium has successfully pursued the development of an internationally supported a molluscan genome project, one that is focused mainly on the freshwater gastropod Biomphalaria glabrata. No one research group has seized control of this project. For this project to succeed, it is necessary to remain a viable, interactive consortium. It is important that scientists from both developed and developing countries step forward to support this initiative.
-This site provides information on design, management and progress of this initiative. Currently, the consortium encourages investigators to pursue external funding available at the national level, towards hypothesis-driven research projects that include a gene discovery component. Individual research groups may combine efforts in national and international settings to apply for large scale resources such as funding for exchange of information and investigators, production of BAC libraries, and sequencing capacity.
-The sequences generated as part of the consortium effort will be released to public databases in a timely fashion.

 News (also see links below)
  • October 2002: Prioritization for BAC library publicly posted (look under snail) by NHGRI
  • September 2003:  Genome size for Biomphalaria glabrata  published (check link below)
  • January 2004: Mitochondrial genome sequence of Biomphalaria glabrata completed
  • August 2004: High quality BAC library (BG-BBa) available at cost from Arizona Genomics Institute
  • August 2004: Biomphalaria glabrata prioritized as genomic sequencing target by NHGRI
  • November 2004: 17,706 trace records (raw single-pass reads of DNA) contributed by WUGSC
  • September 2005: Biomphalaria glabrata genome joint meeting with filarial/schistosome genome networks
  • October 2005: Planning meeting for sequencing strategy at WUGSC, St. Louis MO
  • January 2006: Over 46,000 nucleotide database entries for Biomphalaria glabrata
  • January 2007: RNA, DNA template from selfed BB02 provided to initiate sequencing at WUGSC
  • November 2007: Biomphalaria glabrata genome project progress meeting at ASTMH 2007
  • February 2009: WUGSC releases sequence data from several BACs to NCBI
  • February 2009: WUGSC 454 GS FLX cDNA data (184.6M bases) in NCBI Short Read Archive (SRA)
  • July 2009: WUGSC LS454 gDNA data (17.1Gbases) in NCBI SRA
  • September 2009 WUGSC LS454 paired end gDNA data (6Gbases), > 23x coverage in NCBI SRA
  • SnailDB, Biomphalaria glabrata database, BLAST-able set of clustered ESTs online

Details and additional information
 
Rationale for a focus on Biomphalaria glabrata Open invitation for support or participation
Genome size of Biomphalaria glabrata Mitochondrial genome of Biomphalaria glabrata
 BB02 strain Biomphalaria glabrata for BACs BAC library for Biomphalaria glabrata
Genome sequencing Biomphalaria glabrata rDNA cassette of Biomphalaria glabrata
Members of the consortium  Useful links
Participating research groups