Updated July 2008


NCBI databases : 54050 nucleotide (52624 ESTs)/1 genome/632 protein entries
Genome Project 12879: 116298 records (WGS/EST/454/BES) in the trace archives


 Introduction
-An international consortium has successfully pursued the development of an internationally supported a molluscan genome project, one that is focused mainly on the freshwater gastropod Biomphalaria glabrata. No one research group has seized control of this project. For this project to succeed, it is necessary to remain a viable, interactive consortium. It is important that scientists from both developed and developing countries step forward to support this initiative.
-This site provides information on design, management and progress of this initiative. Currently, the consortium encourages investigators to pursue external funding available at the national level, towards hypothesis-driven research projects that include a gene discovery component. Individual research groups may combine efforts in national and international settings to apply for large scale resources such as funding for exchange of information and investigators, production of BAC libraries, and sequencing capacity.
-The sequences generated as part of the consortium effort will be released to public databases in a timely fashion.

 News (also see links below)
  • October 2002: Prioritization for BAC library publicly posted (look under snail) by NHGRI
  • September 2003:  Genome size for Biomphalaria glabrata  published (check link below)
  • January 2004: Mitochondrial genome sequence of Biomphalaria glabrata completed
  • August 2004: High quality BAC library (BG-BBa) available at cost from Arizona Genomics Institute
  • August 2004: Biomphalaria glabrata prioritized as genomic sequencing target by NHGRI
  • November 2004: 17,706 trace records (raw single-pass reads of DNA sequence) contributed by WUGSC
  • September 2005: Biomphalaria glabrata genome joint meeting with filarial/schistosome genome networks
  • October 2005: Planning meeting for sequencing strategy at WUGSC, St. Louis MO
  • January 2006: Over 46,000 nucleotide database entries for Biomphalaria glabrata
  • January 2007: RNA, DNA template from selfed BB02 provided to initiate sequencing at WUGSC
  • May 2007: First BAC clone from (BS90) Biomphalaria glabrata sequenced (EF418587)
  • August 2007: Over 130,000 nucleotide database entries for Biomphalaria glabrata
  • November 2007: Biomphalaria glabrata genome project progress meeting at ASTMH 2007
  • February 2008: WUGSC will sequence 12 BACs at finishing quality

Details and additional information
 
Rationale for a focus on Biomphalaria glabrata Open invitation for support or participation
Genome size of Biomphalaria glabrata Mitochondrial genome of Biomphalaria glabrata
 BB02 strain Biomphalaria glabrata for BACs BAC library for Biomphalaria glabrata
Genome sequencing Biomphalaria glabrata rDNA cassette of Biomphalaria glabrata
Members of the consortium  Useful links
Participating research groups