glabrata immune responses
Christine Coustau (PI, CR1
CNRS - Christine.Coustau@sophia.inra.fr)
Olga Lucia Baron (PhD student)
Alvaro Baeza Garcia (PhD student)
Nadège Debreuck (technician)
Post-doctoral fellow to be hired
“Interactions biotiques et santé
végétale”, UMR 6243 INRA-CNRS-UNSA
400 Route des Chappes, 06 903 Sophia Antipolis. FRANC
Our long term goal is to better understand immunobiological
interactions between Biomphalaria glabrata
and several pathogens including Schistosoma mansoni.
The specific aims of our current project are
1- To analyse the specificity of B. glabrata immune response .
2- To investigate immune regulation through the functional analysis
of two putative cytokines.
3- To assess the sustainability and specificity of immune priming.
Underlying molecular processes will be investigated using comparative
This is a collaborative project involving
Jean-Marc Reichhart (IBMC, Strasbourg) and André Theron (CBETM,
Perpignan). This project is funded by the French National Research
Agency (ANR) through Dec. 2010.
This research is designed in consultation with other investigators
working with Biomphalaria, to maximize its
impact for future genome-type projects .