Curriculum Vitae
Address:
Department of Biology
University of New Mexico
Albuquerque, NM 87131
(505)277-9338
FAX (505)277-0304
E-mail: maggieww@unm.edu
WEB: http://biology.unm.edu/biology/maggieww/Public_Html/Maggieww.html
Educational History:
B.A., 1971, Stanford University; Stanford, California, English
M.S., 1979, University of Hawaii; Honolulu, Hawaii, Botany Ph.D., 1984, University of Wisconsin-Madison; Madison, Wisconsin, Botany with minor in Biochemistry
Thesis title: Enterokinase Inhibitors in Plants. Sanford Siegel, advisor.
Dissertation title: L-Aspartate transport into pea chloroplasts. Kenneth Keegstra, advisor.
Employment History – Academic positions:
Professor, 2002-present
Vice Chair, Biology, 1997 -1998
Associate Professor of Biology, 1994 - 2002
Assistant Professor of Biology, 1988-1994
NIH Post Doctoral Fellow, 1984-1988, University of Wisconsin, Madison
Graduate student/NIH Trainee, 1979-1984, University of Wisconsin, Madison
Research and Teaching assistant, 1976-1979, University of Hawaii, Honolulu
Employment History - Concurrent positions:
Consultant: in Genomics, including the Computer Sciences/Evolutionary Computing and
Biosensors, Sandia National Laboratories, 1999-2004
Interim director, Southwest Genomics and Biotechnology Alliance, 1999 – 2001
Program director, Microbial Genetics, National Science Foundation, 1998-1999
Professional Recognition:
Academic Awards and Honors:
Andreoli-Woods Lecturer, Cal State LA, 2007
Mujeres Valerosas award, Hispanic Women’s Council, 2006
AAAS Fellow, 2006
Special presidential award for service to SACNAS, 2006
SACNAS Distinguished Scientist Award, 2005
EE Just Lecturer, American Soc for Cell Biology, 2005
NIGMS MORE (Minority Opportunities in Research) Division Working Group, 2005 -2006
Presidential Award for Excellence in Science, Math, and Engineering Mentoring, 2004
Proclamation for service to NM from NM House of Representatives, March 2003
NHGRI Genome Research Review Panel, NHGRI, 2001- 2005
Academic Awards and Honors:
AAAS Latina Scientist 2003
Special service award, National Science Foundation, 1999
Outstanding program officer, BIO/National Science Foundation, 1999
UNM Regents’ Lecturer, 1997-2000
UNM Alumni Faculty Award for outstanding teaching and service to students, 1995
Presidential Young Investigator Award, NSF, 1990-1996
Sigma Xi Honor Society, 1984
Scholarly achievements:
Articles in refereed journals (all papers - cited over 3800 times in scientific literature):
For newer publications and links to them see Publications
A Hidden-state Markov Model for Cell Population Deconvolution
S. Roy, T. Lane, C. Allen, A.D. Aragon, M. Werner-Washburne. Journal of Computational
Biology 13:174901774 (2006)
Multivariate curve resolution of time course microarray data
Peter D Wentzell, Tobias K Karakach, Sushmita Roy, M Juanita Martinez, Christopher P Allen,
and Margaret Werner-Washburne. BMC Computational Biology 7:343 (2006)
Isolation of quiescent and non-quiescent cells from Saccharomyces cerevisiae stationary phase cultures
Chris Allen, Sabrina Büttner, Anthony D. Aragon, Jason A. Thomas, Osorio Meirelles,
Jason E. Jaetao, Don Benn, Stephanie W. Ruby, Marten Veenhuis, Frank Madeo, and
Margaret Werner-Washburne
J Cell Biology 174:89-100 (2006)
Cell-Directed Assembly of the Bio-Nano Interface
HK Baca, C Ashley, E Carnes, D Lopez, J Flemming, D Dunphy, S Singh, Z Chen, N
Liu, H Fan, GP López, SM Brozik, M Werner-Washburne, CJ Brinker
Science 313: 337-341 (2006)
An Automated, Pressure-Driven Sampling Device for Harvesting from Liquid Cultures for
Genomic and Biochemical Analyses. Jerilyn A. Timlin, David M. Haaland, Michael B. Sinclair, Anthony D. Aragon, M.
Juanita Martinez, Margaret Werner-Washburne
BMC Genomics 6:72 (2005)
A Packed Micro Column Approach to a Cell-Based Biosensor
Jeb H. Flemming, Helen K. Baca, Margaret Werner-Washburne, Susan M. Brozik,
Gabriel P. López
Sensors & Actuators 113: 376-381 (2005)
Inferring genetic networks from microarray data
S. Martin, G. Davidson, E. May, J-L Faulon, and M. Werner-Washburne
3rd International IEEE (CSB), pg. 566-569 (2004)
Sleeping Beauty: Quiescence in Saccharomyces cerevisiae.Joseph V. Gray, Gregory A. Petsko, Gerald C. Johnston, Dagmar Ringe, Richard Singer,
and Margaret Werner-Washburne Microbiol. Mol. Biol. Rev. 68:187-206 (2004)
Genomic analysis of stationary phase and exit in Saccharomyces cerevisiae: transcriptional profiling and analysis of essential genes. M. J. Martinez, AB Archuletta, AL Rodriquez, P Wentzell, AD Aragon, CP Allen, S Roy, and M. Werner-Washburne
Molec Biol of the Cell 15: 5295-5305 (2004)
Design, Construction, Characterization, and Application of a Hyperspectral Microarray Scanner
Michael B. Sinclair, Jerilyn A. Timlin, David M. Haaland, and Margaret Werner-Washburne
Applied Optics 43:2079-2088 (2004)
Hyperspectral Imaging of Biological Targets: The Difference A High Resolution Spectral Dimension And Multivariate Analysis Can Make
Jerilyn Timlin, David Haaland, Michael Sinclair, Monica Manginell, Susan Brozik, M. Juanita Martinez, Margaret Werner-Washburne, John Guzowski:
ISBI 2004: 1529-1532 (2004)
Genomics in Neurospora crassa: From One-Gene-One-Enzyme to 10,000 Genes
Edward L. Braun, Donald O. Natvig, Margaret Werner-Washburne and Mary Anne
Nelson
Elsevier Applied Mycology & Biotechnology series, Fungal Genomics 4:295-313 (2004)
The Genome Sequence of the Filamentous Fungus Neurospora crassa
James E. Galagan1, Sarah E. Calvo1, Katherine A. Borkovich2, Eric U. Selker3, Nick D. Read4, William FitzHugh5, Li-Jun Ma1, Serge Smirnov1, Seth Purcell1, Bushra Rehman1, Timothy Elkins1, Reinhard Engels1, Shunguang Wang1, Cydney B. Nielsen1, Jonathan Butler1, David Jaffe1, Matthew Endrizzi1, Dayong Qui1, Peter Ianakiev1, Deborah Bell-Pedersen6, Mary Anne Nelson7, Margaret Werner-Washburne7, Claude P. Selitrennikoff8, John A. Kinsey10, Edward L. Braun11, Alex Zelter4,26, Ulrich Schulte12, Gregory O. Kothe3, Gregory Jedd13, Werner Mewes9,17, Chuck Staben14, Ed Marcotte15, David Greenberg16, Alice Roy1, Karen Foley1, Jerome Naylor1, Nicole Stange-Thomann1, Robert Barrett1, Sante Gnerre1, Michael Kamal1, Manolis Kamvysselis1, Cord Bielke9, Stephen Rudd17, Dmitrij Frishman17, Svetlana Krystofova2, Carolyn Rasmussen18, Robert L. Metzenberg19, David D. Perkins19, Scott Kroken20, David Catcheside21, Weixi Li 14, Robert J. Pratt6, Stephen A. Osmani23, Colin P.C. DeSouza24, Louise Glass18, Marc J. Orbach25, J. Andrew Berglund3, Rodger Voelker3, Oded Yarden26, Mike Plamann27, Stephan Seiler27, Jay Dunlap22, Alan Radford28, Rodolfo Aramayo6, Donald O. Natvig7, Lisa A. Alex29, Gertrud Mannhaupt9, Daniel J. Ebbole30, Michael Freitag3, Ian Paulsen16, Matthew S. Sachs31, Eric S. Lander1,32, Chad Nusbaum1 & Bruce Birren1
Nature422: 859 - 868 (2003)
Identification and removal of contaminating fluorescence from commercial and in-house printed DNA microarrays.
M. Juanita Martinez, Anthony D. Aragon, Angelina Rodriguez, Jose Weber, David Haaland, Jerilyn Timlin, Michael Sinclair, and Margaret Werner-Washburne NAR 31:e18 (2003)
Visual comparison of multiple genome-scale datasets.
Werner-Washburne, M, B. Wylie, E. Fuge, J. Galbraith, J. Weber, and G.S. Davidson.
Genome Research 12: 1564-1573 (2002)
The genomics of stress responses.
A. Gasch and M. Werner-Washburne,
Functional and Integrative Genomics 2:181-192 (2002)
Analysis of the pdx-1 (snz-1/sno-1) region of the Neurospora crassa genome: correlation of
pyridoxine-requiring phenotypes with mutations in two structural genes.
Bean, L.E., W.H. Dvorachek, Jr., E.L. Braun, A. Errett, G.S. Saenz, M.D. Giles, M. Werner-Washburne, M.A. Nelson, and D.O. Natvig.
Genetics 157: 1067-1075 (2001)
Characterization of the SNO and SNZ gene families in Saccharomyces cerevisiae: two
highly conserved, co-regulated gene families involved in a response to nutrient limitation.
P.A. Padilla, E.K.Fuge, M.E. Crawford, A. Errett, M. Werner-Washburne
J. Bact. 180: 5718-5726 (1998)
Yeast bcy1 mutants with stationary phase-specific defects.
V. M. Peck, E.K. Fuge, P. A. Padilla, M.A. Gomez, and M. Werner-Washburne
Current Genetics 32: 83-92 (1997)
Expressed sequences from the conidial, mycelial and sexual stages of Neurospora crassa.
M. A. Nelson, S. Kang, E. L. Braun, M. E. Crawford, P. L. Dolan, P. M. Leonard,
J Mitchell, A. M. Armijo, L. Bean, E. Blueyes, T. Cushing, A. Errett, M. Fleharty,
M Gorman, K. Judson, R. Miller, J. Ortega, I. Pavlova, J. Perea, S. Todisco, R. Trujillo,
J. Valentine, A. Wells, M. Werner-Washburne, S Yazzie, and DO Natvig.
Fungal Genetics and Biology 21: 348-363 (1997)
A stationary-phase gene in Saccharomyces cerevisiae is a member of a novel, highly conserved gene family.
Edward L. Braun, Edwina K. Fuge, Pamela A. Padilla, and Margaret Werner-Washburne
Journal of Bacteriology 178: 6865-6872 (1996)
Stationary Phase in Saccharomyces cerevisiae
Margaret Werner-Washburne, E. L. Braun, M.E. Crawford, and V.M.Peck
Molecular Microbiology 19:1159-1166 (1996)
Protein synthesis in long-term stationary phase cultures of Saccharomyces cerevisiae.
Edwina K. Fuge, Edward L. Braun, and Margaret Werner-Washburne
Journal of Bacteriology 176:5802-5813. (1994)
Stationary phase in the yeast Saccharomyces cerevisiae.
M. Werner-Washburne, E. Braun, G.C. Johnston, and R. A. Singer.
Microbiological Reviews 57:383-401. (1993)
Isolation and characterization of AAP1; a gene encoding an alanine/arginine
aminopeptidase in yeast.
Dan Caprioglio, Christopher Padilla, and Margaret Werner-Washburne.
Journal of Biological Chemistry 268:14310-14315. (1993)
Heat-shock mediated cell-cycle blockage and G1 cyclin expression in the yeast
Saccharomyces cerevisiae.
A.Rowley, B. Butler, M. Werner-Washburne, G.C. Johnston, and R.A. Singer.
Molecular and Cellular Biology 13:1034-1041. (1992)
The translation machinery and 70 kilodalton heat shock protein cooperate in protein synthesis.
R. J. Nelson, T. Ziegelhoffer, C. Nicolet, M. Werner-Washburne, and E. A. Craig.
Cell 71: 97-105.(1992)
Bcy1, the regulatory protein of cAMP- dependent protein kinase, is differentially modified in
response to the physiological status of the cell.
M. Werner-Washburne, David Brown, and Edward Braun.
Journal of Biological Chemistry 266:19704-19709. (1991)
Yeast Hsp70 RNA levels vary in response to the physiological status of the cell.
M. Werner-Washburne, J. Becker, J. Kosic-Smithers, and E. A. Craig.
Journal of Bacteriology 171: 2680-2688. ( 1989)
Expression of members of the S.cerevisiae HSP70 multigene family.
M. Werner-Washburne and E.A.Craig.
Genome 31 :684-689. ( 1989)
SSC1, an essential member of the yeast HSP70 multigene family, encodes a mitochondrial protein.
E.A. Craig, J. Kramer, J. Shilling, M. Werner-Washburne, S. Holmes, J. Kosic-Smithers,
and C.M. Nicolet.
Molec. Cell Biol .9:3000-3008. (1989)
A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides.
R. Deshaies, B.D. Koch, M. Werner-Washburne, E. Craig, and R. Schekman.
Nature 332:800-805. (1988)
Complex interactions among members of an essential subfamily of Hsp70 genes in yeast.
M. Werner-Washburne, D.Stone, and E.A. Craig.
Mol. Cell Biol. 7: 2568-2577.(1987)
L-Aspartate transport into pea chloroplasts. Kinetic and inhibitor evidence for multiple transport systems.
M. Werner-Washburne and K. Keegstra
Plant Physiol. 78: 221-227. (1985)
Precursors to two chloroplast proteins bind to the outer chloroplast membrane prior to import.
K. Cline, M. Werner-Washburne, T.H. Lubben, and K. Keesgtra.
J.Biol. Chem. 260: 3691-3696. (1985)
Adenine nucleotide translocase dependent anion transport in pea chloroplasts.
G.Woldegiorgis, S.Voss, E.Shrago, M. Werner-Washburne, and Kenneth Keegstra.
Biochem. Biophys. Acta 810: 340-345.(1985)
Thermolysin is a suitable protease for probing the surface of intact pea chloroplasts.
K.Cline, M. Werner-Washburne, J. Andrews, and K. Keegstra.
Plant Physiol. 75: 675-678. (1984)
The chloroplast envelope: Is it homologous with the double membranes of mitochondria and gram- negative bacteria?
K. Keegstra, M. Werner-Washburne, K. Cline, and J. Andrews.
J. of Cellular Biochem. 24: 55-68. (1983)
Analysis of pea chloroplast inner and outer envelope membrane proteins by two-dimensional gel electrophoresis and their comparison with stromal proteins.
M. Werner-Washburne, K. Cline, and K. Keegstra.
Plant Physiol. 73: 569-575. (1983)
An adenine nucleotide-phosphoenolpyruvate counter-transport system in C3 and C4 plant chloroplasts.
G. Woldegiorgis, S. Voss, E. Shrago, M. Werner-Washburne, and K. Keegstra.
Biochem. Biophys. Res. Comm. 116:945-951. (1983)
Survey of plants for enterokinase inhibitors.
M. Werner-Washburne, A.Lau, and H. Ako.
Biochem. Biophys. Res. Com. 92: 1243-1249. (1980)
Articles appearing as chapters in edited volumes:
Robust methods for microarray analysis
George S. Davidson, Shawn Martin, Kevin W. Boyack, Brian N. Wylie, Juanita Martinez, Anthony Aragon, Margaret Werner-Washburne, Mónica Mosquera-Caro, Cheryl Willman
Genomics and Proteomics Engineering in Medicine and Biology, IEEE ed. Metin Akay; pp. 99-130 (2007)
Stationary phase in the yeast Saccharomyces cerevisiae.
E. K. Fuge and M. Werner-Washburne. 1997In "Yeast Stress Responses", Hohmann S and Mager WH, eds., Molecular Biology Intelligence Unit, R.G. Landes Company, Austin, TX (1997),
pp. 53-74
Molecular requirements for protein translocation into the endoplasmic reticulum.
R.Deshaies, J.Rothblatt, S.Sanders, M. Werner-Washburne, E.Craig, and R.Schekman.
p. 187-198. In Bissell, Deho, Sironi, Torriani (ed.), Gene Expression and Regulation: The
Legacy of Luigi Gorini. Elsevier, N.Y. ( 1988)
Metabolite transport across the chloroplast envelope.
M. Werner-Washburne and K. Keegstra.
Oxford Surveys of Plant Mol. and Cell Biol. 2:123-145. (1985)
Dicarboxylate transport into isolated chloroplasts. The evidence for multiple carrier systems.
M. Werner-Washburne and K. Keegstra.
In Proc. 14th Steenbock Symposium "Nitrogen Fixation and CO2 Metabolism." P.W.
Ludden and J.E. Burris, eds. Elsevier Publ., N.Y. pp. 389-397.(1985)
Other writings (video/patents/government reports/articles):
A Perfect Mix
Findings Magazine (NIGMS- NIH)
Fall, 2003
http://biology.unm.edu/biology/maggieww/Public_Html/PerfectMix.pdf
Interagency Report on the Federal Investment in Microbial Genomics
Coordinated and partially written by M. Werner-Washburne
Biotech. Research Working Group, subcommittee of the NSTC Biotechnology Committee
Office of Science and Technology Policy, 2000
http://www.ostp.gov/html/microbial/2000microbial/nsf00203_1.htm
Following the Coil of Life
Albuquerque Tribune, January 1, 2000
http://biology.unm.edu/biology/maggieww/Public_HTML/followingthecoil.htm
Southwest Genomics and Biotechnology Alliance White Paper
(http://www.sandia.gov/swgaba), July 1999
The mystery of an ancient gene NSF/PBS/LANL supported video (28 minutes)
Produced by Denise Wallen and Larry Walsh.
December, 1997. Shown nationally, April 1998.
Recent talks/presentations
Changing your road to success to a path with heart
CalStateLA
Andreoli-Woods Lecture
Los Angeles, CA, May 2007
Genomics of the quiescent state in yeast
U Washington Genome Center
Seattle, Washington, March 2007
Mentoring
U Washington Department of Biology
Seattle, Washington, March 2007
Genomics of the quiescent state in yeast
U Montana
Missoula, MT, April, 2007